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Egg Consumption eggs may be associated with reduced risk of stroke (2016-11-09)

The possible relationship between dietary cholesterol and cardiac outcomes has been scrutinized for decades. However, recent reviews of the literature have suggested that dietary cholesterol is not a nutrient of concern.

'Previously, the Dietary Guidelines for Americans recommended that cholesterol intake be limited to no more than 300 mg/day. The 2015 DGAC will not bring forward this recommendation because available evidence shows no appreciable relationship between consumption of dietary cholesterol and serum cholesterol, consistent with the conclusions of the AHA/ACC report.2 35 Cholesterol is not a nutrient of concern for overconsumption. (Scientific Report of the 2015 Dietary Guidelines Advisory Committee - Link...)

Thus, researchers conducted a meta-analysis of egg intake (a significant contributor to dietary cholesterol) and risk of coronary heart disease (CHD) and stroke.
A comprehensive literature search was conducted through August 2015 to identify prospective cohort studies that reported risk estimates for egg consumption in association with CHD or stroke.
Random-effects meta-analysis was used to generate summary relative risk estimates (SRREs) for high vs low intake and stratified intake dose–response analyses. Heterogeneity was examined in subgroups where sensitivity and meta regression analyses were conducted based on increasing egg intake.

A 12% decreased risk (SRRE = 0.88, 95% confidence interval [CI], 0.81–0.97) of stroke was observed in the meta-analysis of 7 studies of egg intake (high vs low; generally 1/d vs <2/wk), with little heterogeneity (p-H = 0.37, I2 = 7.50).

A nonstatistically significant SRRE of 0.97 (95% CI, 0.88–1.07, p-H = 0.67, I2 = 0.00) was observed in the meta-analysis of 7 studies of egg consumption and CHD.

No clear dose–response trends were apparent in the stratified intake meta-analyses or the meta regression analyses.

Based on the results of this meta-analysis, consumption of up to one egg daily may contribute to a decreased risk of total stroke, and daily egg intake does not appear to be associated with risk of CHD.

See also
Egg consumption and risk of coronary heart disease and stroke (2013-02-13)
Link...

For more information
Journal of the American College of Nutrition
Meta-analysis of Egg Consumption and Risk of Coronary Heart Disease and Stroke
Link...

Dietary Guidelines for Americans 2015-2020 Eighth edition
Link...

Scientific Report of the 2015 Dietary Guidelines Advisory Committee
Link...

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