The possible relationship between dietary
cholesterol and cardiac outcomes has been
scrutinized for decades. However, recent reviews of
the literature have suggested that dietary
cholesterol is not a nutrient of concern.

'Previously, the Dietary Guidelines for
Americans recommended that cholesterol intake be
limited to no more than 300 mg/day. The 2015 DGAC
will not bring forward this recommendation because
available evidence shows no appreciable relationship
between consumption of dietary cholesterol and serum
cholesterol, consistent with the conclusions of the
AHA/ACC report.2 35 Cholesterol is not a nutrient of
concern for overconsumption. (Scientific Report of
the 2015 Dietary Guidelines Advisory Committee -
Link...)
Thus, researchers conducted a meta-analysis of egg
intake (a significant contributor to dietary
cholesterol) and risk of coronary heart disease (CHD)
and stroke.
A comprehensive literature search was conducted
through August 2015 to identify prospective cohort
studies that reported risk estimates for egg
consumption in association with CHD or stroke.
Random-effects meta-analysis was used to generate
summary relative risk estimates (SRREs) for high vs
low intake and stratified intake dose–response
analyses. Heterogeneity was examined in subgroups
where sensitivity and meta regression analyses were
conducted based on increasing egg intake.
A 12% decreased risk (SRRE = 0.88, 95% confidence
interval [CI], 0.81–0.97) of stroke was observed in
the meta-analysis of 7 studies of egg intake (high
vs low; generally 1/d vs <2/wk), with little
heterogeneity (p-H = 0.37, I2 = 7.50).
A nonstatistically significant SRRE of 0.97 (95% CI,
0.88–1.07, p-H = 0.67, I2 = 0.00) was observed in
the meta-analysis of 7 studies of egg consumption
and CHD.
No clear dose–response trends were apparent in the
stratified intake meta-analyses or the meta
regression analyses.
Based on the results of this meta-analysis,
consumption of up to one egg daily may contribute to
a decreased risk of total stroke, and daily egg
intake does not appear to be associated with risk of
CHD.
See also
Egg consumption and risk of coronary heart disease
and stroke (2013-02-13)
Link...
For more information
Journal of the American College of Nutrition
Meta-analysis of Egg Consumption and Risk of
Coronary Heart Disease and Stroke
Link...
Dietary Guidelines for Americans 2015-2020 Eighth
edition
Link...
Scientific Report of the 2015 Dietary Guidelines
Advisory Committee
Link...
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