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Sleep benefits the consolidation of psychological
memory, and there are hints that sleep likewise
supports immunological memory formation.
Comparing psychological and immunological domains,
researchers make the case for active system
consolidation that is similarly established in both
domains and partly conveyed by the same
sleep-associated processes.
In the psychological domain, neuronal reactivation
of declarative memory during slow-wave sleep (SWS)
promotes the redistribution of representations
initially stored in hippocampal circuitry towards
the neocortex and striatum for long-term storage.
In the immunological domain, slow-wave sleep seems
to favor the redistribution of antigenic memories
initially held by antigen-presenting cells, to
persisting T cells serving as a long-term store.
In both systems, the consolidation of memory is
mediated by slow-wave sleep that suppresses
cholinergic and cortisol activity, and enhances
proinflammatory signals.
Because storage capacities are limited in both
systems, system consolidation presumably reduces
information by abstracting gist for long-term
storage.
Although responding to different environmental
events, the central nervous system and the immune
system share basic functions of memory.
See also
Vitamin A supplementation may cause the immune
system to forget past infections (2015-07-19)
link...
For more information
Cell PRESS
System Consolidation During Sleep – A Common
Principle Underlying Psychological and Immunological
Memory Formation
Jürgen Westermann, Tanja Lange, Johannes Textor, Jan
Born.
http://dx.doi.org/10.1016/j.tins.2015.07.007
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