New research in The FASEB Journal suggests that
chronic inflammation from diets deficient in
nutrients contribute to weight regardless of the
intake of macronutrients.
A new report appearing in the August 2015 issue of
The FASEB Journal suggests that inflammation induced
by deficiencies in vitamins and minerals might be
the culprit. In this report, researchers show that -
in some people - improvement results in many of the
major markers of health when nutritional
deficiencies are corrected. Some even lost weight
without a change in their diet or levels of
activity.
"It is well known that habitual consumption of poor
diets means increased risk of future disease, but
clearly this is not a compelling enough reason for
many to improve their eating habits," said Bruce
Ames, Ph.D., a senior scientist at Children's
Hospital Oakland Research Institute, director of
their Nutrition and Metabolism Center, and a
professor emeritus of Biochemistry and Molecular
Biology at the University of California, Berkeley.
"However, a relatively easy intervention with
something like the nutrient bar used in this study
may help people to realize the positive impact that
a diet with adequate nutrition can have in their
daily lives, which may be a stronger incentive for
change."
To make their Ames and colleagues undertook three
clinical trials in which adults ate two nutrient
bars each day for two months. Participants acted as
their own controls, meaning that changes in a wide
variety of biochemical (e.g., HDL-c, LDL-c, insulin)
and physical (e.g., blood pressure, weight)
measurements were recorded in each individual over
the two-month period. People who were
overweight/obese moved in a healthier metabolic
direction (e.g., improved HDL, LDL, insulin,
glucose, etc.), and some lost weight by just eating
small, low-calorie, nutrient bars each day for two
months, without any additional requirements.
"If being healthy was as simple as 'losing weight'
or 'keeping thin,' our ancient ancestors who lived
in times of extreme food scarcity might still be
with us today," said Gerald Weissmann, M.D.,
Editor-in-Chief of The FASEB Journal. "This report
shows that what you eat is as important, if not
more, than how much you eat and how many calories
you burn in the gym."
For more information
A multicomponent nutrient bar promotes weight loss
and improves dyslipidemia and insulin resistance in
the overweight/obese: chronic inflammation blunts
these improvements
http://www.fasebj.org/content/29/8/3287.abstract
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